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Fig. 2. Heat maps to display the expression properties of multi-tissue gene
clusters in cardiac and white skeletal muscle. 30°C-acclimated carp were
exposed to reduced temperatures for increasing lengths of time, as indicated
by the blue triangles at the top of the figure. We collected fully replicated
data from seven different tissues and used this to produce a cluster of genes
with tissue-specific patterns of expression, all as described elsewhere
(Gracey et al., 2004). The
rows in the heat maps in A represent genes across both cardiac and skeletal
muscle and the columns represent array data for different temperature/time
points. (A) Cluster 8 (see Fig.
1), which included genes with decreased expression at all three
reduced temperatures in skeletal muscle. These responses are specific to
skeletal muscle since cardiac muscle showed no such change. The panel to the
side provides a list of the most relevant genes within the `Cell motility' GO
category. (C) Cluster 11 where the predominant response in skeletal muscle is
upregulation. (B) Time course of changes in transcript levels of two notable
genes included in heatmap C. The vertical dotted lines in B separate the three
cooling regimes, down to 23°C, to 17° and to 10°C, from left to
right for each muscle tissue. The response of both genes is graded and
transitory.
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