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Fig. 5. Microadaptations of transcript expression relate to the training effect.
Model of the increase in (mitochondrial) RNA and endurance performance with
repetition of exercise. Each bout of exercise leads to an overshoot of
transcript levels in the recovery phase from fatiguing exercise (
RNA),
which leads via translation to a microadaptation of the encoded
protein and related structure. This relays to the gradual accumulation
() of mitochondrial volume density and the improved oxidative capacity
with repetition of endurance exercise. A match of transcriptional, structural
and functional parameters is observed in recruited muscle groups between
untrained and endurance-trained steady states. Black stippled and solid lines
indicate the evolution of RNA levels and performance, respectively, during the
training.
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