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Fig. 4. Effect of depletion of Ca2+ mitochondrial pools on
tBHP-evoked Ca2+ release in pancreatic acinar cells. (A)
Cells were perfused with 0.5 µmol l-1 FCCP, followed by
perfusion with 1 mmol l-1 tBHP, in Ca2+-free
medium. (B) Cells were perfused with 1 mmol l-1 tBHP,
followed by perfusion with 0.5 µmol l-1 FCCP, in
Ca2+-free medium. Traces are representative of 27 and 18 such cells
taken from 7 and 6 different experiments, respectively.