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Fig. 1. Maximum aerobic capacity (VO2max) measured during forced exercise in a hypoxic (14% O2), normoxic (21% O2) and hyperoxic atmosphere (30% O2) for 59 mice from lines selected for high voluntary wheel running (S) and their non-selected control lines (C). Each point represents the highest 60-s average obtained in two measurements on the treadmill performed on consecutive days (see Materials and methods). (Left panels) Aerobic capacity in relation to selection history - i.e. S (closed circles) versus C (open circles). Adjusted means for S and C in each PO2 are listed in Table 2. (Right panels) The same graph, but highlighting individuals with the mini-muscle phenotype (all in S lines) versus normal phenotypes. Effects of size, selection history and mini-muscle are summarized in Table 2.





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