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Fig. 2. Extension of Kleiber's 3/4-power law for the metabolic rate of mammals to over 27 orders of magnitude from individuals (blue circles) to uncoupled mammalian cells, mitochondria and terminal oxidase molecules, CcO of the respiratory complex, RC (red circles). Also shown are data for unicellular organisms (green circles). In the region below the smallest mammal (the shrew), scaling is predicted to extrapolate linearly to an isolated cell in vitro, as shown by the dotted line. The 3/4-power re-emerges at the cellular and intracellular levels. Figure taken from West et al. (2002b) with permission.





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