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Fig. 4. Changes in transepithelial voltage (Vte) and short circuit current (Isc) in response to a hypotonic stress (decrease of Ringer osmolarity from 315 mOsm to 175 mOsm). - sign of Vte refers to the mucosa (grounded); - sign of Isc indicates current flowing from mucosal to serosal side. Vte time course represents the registered trace, while Isc time course was performed by keeping the preparation `short circuited' every 5 min. Representative time course of N=20 trials.





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