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Fig. 7. Influence of HDAC inhibitor-induced histone H3 hyperacetylation on hsp mRNA expression during aging. (A,B) hsp22 mRNA basal expression in young flies (6-day old; A) and old flies (30-day old; B) after HDAC inhibitor treatment. (C,D) hsp70 mRNA basal expression in young flies (6-day old; C) and old flies (30-day old; D) after HDAC inhibitor treatment. (E,F) hsp22 mRNA inducible expression in young flies (6-day old; E) and old flies (30-day old; F) after HDAC inhibitor treatment. (G,H) hsp70 mRNA inducible expression in young flies (6-day old; G) and old flies (30-day old; H) after HDAC inhibitor treatment. Experiments were performed in triplicate. Bars represent means ± S.E.M. For basal expression (A-D), *P<0.05 and **P<0.01, versus untreated control. For inducible expression (E-H), *P<0.05 and **P<0.01, versus RMHS. Abbreviations as in Fig. 5.





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