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Fig. 2. Electron microscopy of flight muscle from fln0,
wild-type and transgenic flies. All pictures are from 25-day-old adult
IFM. (A,B), fln0; (C,D), wild-type; (E,F),
P{fln+}0.2; (G,H),
P{fln+}2.2; (I and J),
P{fln+}0.2. A, C, E, G, I are longitudinal
sections; B, D, F, H, and J are cross sections. Note that the highly disrupted
sarcomere structure in fln0 (in A,B) is no longer evident
in the rescued line. However, there are fewer thick filaments per myofibril
cross-sectional area. G and H, flies expressing four copies of
fln+ have normal IFM. I and J, are examples of occasional
defects seen in P{fln+}0.2 flies. Bar, 0.5
µm.