spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 8. Effects of WIN 55,212-2 and 2-AG ether on activation and inactivation of the Na+ currents. (A) Voltage dependence of activation before and after superfusion with 10 µmol l–1 WIN 55,212-2. V1/2=–48.6 mV, k=–5.1 mV for control (open squares), V1/2=–37.0 mV, k=–5.0 mV for WIN 55,212-2 (filled circles). (B) Voltage dependence of inactivation before and after superfusion with 10 µmol l–1 WIN 55,212-2 (filled circles). V1/2=–76.9 mV, k=8.1 mV for control (open squares), V1/2=–94.4 mV, k=9.0 mV for WIN 55,212-2. (C) V1/2 of activation before (white bars) and after superfusion with each drug (hatched bars). (D) V1/2 of inactivation before (white bars) and after superfusion with each drug (hatched bars). Values are means ± S.E.M. Numerals within parentheses are number of the cells sampled.





Right arrow Return to article