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Fig. 7. Effects of WIN 55,212-2 and 2-AG ether on the Na+ currents. (A) Reversible inhibition of the Na+ current by 10 µmol l–1 WIN 55,212-2. The currents were elicited by a 20 ms pulse from a holding potential of –84 mV to a test potential of –24 mV. The current traces labelled a–c were obtained at the times indicated by the same letter on the time course. (B) Representative example of time course of the current signal. (C) Na+ current magnitudes before and after superfusion with each drug. Values are means ± S.E.M. Numerals within parentheses are number of the cells sampled.





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