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Fig. 5. Voltage dependence of steady-state inactivation of the Na+
currents. (A) The dependence was determined by measuring peak current elicited
by a single depolarization to 34 mV from a range of 200 ms conditioning
voltages. (B) V1/2=79.8 mV, k=8.2 mV for
perforated recording (filled circles),
V1/2=86.3 mV, k=9.4 mV
for conventional recording (open circles). (C)
V1//2=98.4 mV, k=9.6 mV for 0.5 mmol
l-1 GTP
S (filled triangles),
V1/2=86.1 mV, k=10.0 mV for 1 mmol
l1 GDPßS (open triangles). For comparison, the broken
line for conventional recording is plotted in B. The values are means ±
S.E.M. obtained from 714 cells.