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Fig. 8. Time course of recovery of K+ current from inactivation. (A)
Upper panel: protocol of the double pulses stimulation. Two-step
depolarisations from the holding potential of –70 mV to +30 mV with the
interval of 
t were applied. Lower panel: K+
currents in response to double-pulse stimulation (t=10 s).
Amplitude of the 2nd K+ current (right) was 
50% of the 1st
current (left). (B) Relationship between the recovery of K+ current
amplitude and t. The curve was fitted with an equation of
experimental decay,
I(t)/I0=1–exp(–t/
),
where I(t)/I0 is the relative
amplitude of K+ current after an interval time of t
(s), and is the time constant in s for K+ current recovery.
The value of is 13.2 s. The bath solution was N-Ca-free-ASW containing 4
µmol l–1 TTX, and the pipette solution was K-asp. Cell
membrane capacitance (Cm)=143.2 pF.
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