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Fig. 8. Glibenclamide blocks amaranth transport. Eight tubules were arranged
radially for classical (Ramsay) secretion assays
(Dow et al., 1994): the
bathing drops are just out of shot. Droplets were collected every 10 min, and
so the colour of the droplets provides a correlate of real-time amaranth
transport. (A) Secreted drops before glibenclamide was added. (B) Secreted
droplets 35 min after glibenclamide was added to the final concentrations (in
mmol l-1) shown. Drops labelled `C' had no glibenclamide added to
the bubbles. The concentration of amaranth in the reservoir bubbles was 2
µmol l-1.