spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 4. irk3 expression is localised to the principal cells of the tubule main segment by in situ analysis. (A,B) Low-power views, showing expression in the main segment (MS), lower segment (LS) and ureter (U) of the tubule but not in the initial segment (IS) of the anterior tubule or the hindgut (HG). (C) High-power view of the anterior tubule initial segment, showing no expression. By contrast, the initial segment of the posterior tubule (D) shows staining as intense as the main segment. (E) High-power view of the lower tubule and ureter, showing expression throughout. (F) High levels of expression in nurse cells and oocytes. (G,H) High-power view of tubule main segment, showing that expression is confined to principal cells (PC) but is not in the very narrow stellate cells (SC). The two cell types can be distinguished because stellate cell nuclei are smaller than those of principal cells (arrows). Sense controls did not produce any staining (data not shown). Tubule diameter can be taken as 35 µm throughout.





Right arrow Return to article