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Fig. 2. Effects of bolus intra-arterial injections of ET-1 on the maximum change in mean arterial systemic and pulmonary pressures, (A) Psys and (D) Ppul, respectively; systemic and pulmonary blood flows, (B) sys and (E) pul; systemic and pulmonary vascular conductances, (C) Gsys and (F) Gpul as a function of the amount of peptide injected. Data points show means ± S.E.M. for eight (systemic variables) and six (pulmonary variables) individual experiments. The asterisks denote a significant difference (P<0.05) from the pre-injection value.





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