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Fig. 1. The analysis method for determining phasic peak discharge rate and magnitude of spike frequency adaptation of individual intrapulmonary chemoreceptors. (A) The CO2 stimulus waveform delivered to the lungs in the ventilatory gas. (B) Raster plot of spike occurrence times as vertical hash marks (this example was recorded from a lovebird IPC). (C) A schematic representation of spike discharge frequency vs time – a cycle triggered stimulus histogram. Definitions of peak frequency and magnitude of spike frequency adaptation are indicated (both measurements are in units of frequency: s–1).





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