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Fig. 6. The steady-state activation and inactivation properties of the sodium
currents required to produce repetitive firing in the model (dotted lines) are
compared with those reported in situ (solid lines). The
V50s of activation and inactivation required were taken as
the coordinates in Fig. 4 of
the point that represents the minimum distance from the values obtained in
situ. Note that for repetitive firing to occur, there must be a
simultaneous right shift in inactivation and a left shift in activation.