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Fig. 9. The effects of
-CTx AuIB and
-CTx MII on submucosal ganglia
can be reproduced on myenteric ganglia, confirming that
3ß2- and
3ß4-containing nAChRs are expressed in both enteric plexuses. (A)
High-resolution image of a myenteric ganglion (inverted grey scale). The
position of the stimulation electrode is shown schematically. (B) Pixel map of
the NeuroCCD-SM camera depicting, in dark grey, the area of interest. Notice
that the highlighted area is considerably bigger than the ganglion itself. (C)
Experimental protocol. (D) Spatially averaged optical outputs from the
dark-grey pixels in B, represented by bars whose heights indicate the
amplitude of the voltage change under each experimental condition.
Magnification, 40x. All signals were high-pass filtered at 9.8 Hz.