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Fig. 8. {alpha}7-nAChRs contribute substantially to the evoked response in submucosal neurones. (A) High-resolution image of a submucosal ganglion (inverted grey scale), showing the individual neurones identified by numbers. The position of the stimulation electrode is shown schematically. (B) Pixel map of the NeuroCCD-SM camera depicting, in red, the area of interest. (C) Experimental protocol. (D) Spatially averaged optical outputs from the red pixels in B (represented by bars whose heights indicate the amplitude of the voltage change under each experimental condition in the row labelled `Ganglion') and from the pixels that outline individual neurones (`Cells'). Magnification, 100x. `Ganglion' signals were high-pass filtered at 6.6 Hz. `Cell' traces were unfiltered.





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