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Fig. 6. Specific ion conductance (Gm) of the wild-type and {Delta}F508 mutant cystic fibrosis transmembrane-conductance regulator (CFTR) in forskolin-stimulated transfected mouse fibroblast cells. The untreated mutant cells have very low conductance compared with the wild type, while cells exposed to 300 mmol l–1 of the indicated osmolytes had conductance rates as great or greater than the wild type (modified from Howard et al., 2003). *Significant difference compared to wild type.





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