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Fig. 6. Specific ion conductance (Gm) of the wild-type and
F508 mutant cystic fibrosis transmembrane-conductance regulator (CFTR)
in forskolin-stimulated transfected mouse fibroblast cells. The untreated
mutant cells have very low conductance compared with the wild type, while
cells exposed to 300 mmol l1 of the indicated osmolytes had
conductance rates as great or greater than the wild type (modified from
Howard et al., 2003).
*Significant difference compared to wild type.