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Fig. 6. Preliminary working model of Na+ absorption by killifish gills. Apical Na+ uptake occurs via NHE2 in exchange for H+ supplied by CA2. Active transport of Na+ across the basolateral surface is accomplished by Na+,K+-ATPase. Na+ may also leave the cell in symport with HCO3– through NBC1 operating in efflux mode. V-ATPase may pump H+ across the basolateral surface to help maintain intracellular acid–base balance.





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