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Fig. 8. Schematic diagrams of the four mitochondrion-rich cell types, showing intracellular localization of Na+/K+-ATPase (red), Na+/K+/2Cl- cotransporter (NKCC, cyan) and cystic fibrosis transmembrane conductance regulator (CFTR, green). The movements of ions are focused on Na+ and Cl-, and a K+ channel recycling K+ is omitted in order to simplify the diagrams. A Cl- channel (gray) is added on the basolateral membrane of the type-II cell, although its presence was not examined in this study. The presumed interrelationship among the four cell types are indicated by arrows A-E.





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