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Fig. 4. Recordings of effects of NOS inhibitors on peristaltic contractions of
reduced preparations. L-NAME (N(
)-nitro-L-arginine methyl
ester) dose-dependently reduced both the amplitude of peristaltic waves and
basal tension whereas aminoguanidine, in a separate preparation, increased
peristaltic waves without affecting basal tension. Dotted line indicates
initial basal tension.