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Fig. 5. Tetanic force versus sarcomere length recorded in mouse single
muscle fibers. (A) Force expressed in units of the tetanic force recorded near
2.4 µm sarcomere length. The straight line is linear regression of force
upon sarcomere length for values between 2.35 and 4.00 µm sarcomere length.
Asterisks along the ascending limb are calculated force values based on the
assumptions described in text. (B) Schematic illustration of different degrees
of overlap between thick (A) and thin (I) filaments. OS,
single filament overlap; OD, double filament overlap;
OC, compression of thick filaments when colliding with
Z disks at short (<1.7 µm) sarcomere lengths. Reproduced, with
permission, from Edman and Reggiani
(1987). For further
information, see text.
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