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Fig. 2. Effect of isoproterenol (ISO) on SR Ca2+ uptake. (A) INCX elicited by 10 mmol l–1 Caffeine after a preceding 10 s depolarization to –70, –30 or –10 mV in the absence (CON) and the presence of 1 µmol l–1 ISO. (B) Time integrals of the currents in A. The experimental conditions are indicated above each trace and the time scale bar corresponds to 5 s.





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