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Fig. 5. The effect of increasing the duration of severe hypoxia on the input pressure PIN required to maintain a resting cardiac output of 16–17 ml min–1 kg–1. (A) PIN recorded prior to max1 and prior to max2; (B) the change in resting PIN between max1 and max2 (N=6–7 in each group). *Significant difference (P<0.05) identified using repeated-measures ANOVA. One-way ANOVA did not reveal any significant differences in the change in PIN between treatments.





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