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Fig. 3. (A) Cumulative concentrationresponse curve showing the effect of
3-morpholinosydnonimine (SIN-1; from 107 to
105 mol l1) on stroke volume
(VS) and stroke work (WS) in isolated
and perfused icefish hearts. (B) Effects of 3-morpholinosydnonimine (SIN-1;
105 mol l1) before and after treatment
with superoxide dismutase (SOD; 10 i.u. ml1) on stroke
volume (VS) and stroke work (WS) in
isolated and perfused icefish hearts. Percentage changes were evaluated as
means ± S.E.M. of five (A) and four (B) experiments.
Asterisks indicate values significantly different from the control value:
*P<0.05; **P<0.025.