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Fig. 7. The simulated pattern of D- and L-glucose
radiolabeled probe absorption at the apical membrane in the presence of an
initial high substrate concentration (100 mmol l-1) varies
according to whether absorption is primarily mediated or primarily passive.
The same four different situations as shown in
Fig. 6 are modeled, but the
starting concentration of unlabeled D-glucose is 100 times higher.
Notice that when passive absorption dominates (Aiv,Biv), the predicted
cumulative absorption of D- and L-glucose probes as a
function of time (Aiv) are much more similar than when mediated absorption
dominates (Aiii). Analogously, when passive absorption dominates, the
predicted absorption rates of D- and L-glucose probes as
a function of time (Biv) are much closer than when mediated absorption
dominates (Biii).
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