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Fig. 5. Dose–response of the effects of cGMP on the basolateral membrane voltage Vbl (A), and the input resistance Rpc (B) of principal cells in isolated Malpighian tubules of A. aegypti. The insert in A illustrates the usual biphasic response of Vbl to 500 µmol l–1 cGMP. Values are means ± S.E.M.; the number of principal cells is indicated for each data point; *P<0.05, paired Student's t-test. Open circles, steady state depolarization; closed circles, peak depolarisation.





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