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Fig. 9. Correlation between TnT and TnI protein isoforms. The proportion of each
TnI isoform is plotted as a function of the proportion of TnT3 (1 -
proportion TnT1). (A) TnI1, which is expressed in fast
muscles (Mykles, 1985a,
1997), was a minor isoform
only observed in two samples and was not significantly correlated with TnT
composition. (B) The relative amount of TnI2 was negatively
correlated with the proportion of TnT3 (P<0.0001;
r2=0.79). (C) The relative amount of TnI3 was
positively correlated with the proportion of TnT3
(P<0.002; r2=0.58). (D) The proportion of
TnI4 was positively correlated with the proportion of
TnT3 (P<0.0043; r2=0.41) but was
present in lower amounts than TnI3. Arrows at the bottom of the
figure indicate that lower amounts of TnT3 (left side of graphs)
are characteristic of S2 fibers, while greater amounts of
TnT3 (right side of graphs) are characteristic of S1
fibers. Single fiber samples are indicated by filled circles, while samples
from small bundles of fibers are represented by open circles.
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