spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

Right arrow Help viewing high resolution images
Right arrow Return to article

(Downloading may take up to 30 seconds.
If the slide opens in your browser, select File -> Save As to save it.)
Click on image to view larger version.



Fig. 6. The effect of D1-selective antagonists on dopamine-stimulated cAMP production in the albumen gland of H. duryi. All agents were used at a concentration of 10 µmol l-1 and applied to the glands for 10 min. For the dopamine plus antagonist combinations, the glands were first pre-incubated in antagonist for 20 min.Dopamine (DA) significantly increased cAMP levels in the albumen glands compared with untreated control glands (CON). (A) The D1-selective antagonist SCH23390 had no effect on basal cAMP levels but significantly inhibited dopamine-stimulated cAMP production (*P<0.001, Tukey test). (B) The D1-selective antagonist SKF83566 significantly suppressed dopamine-stimulated cAMP production and had no effect on basal cAMP levels (*P<0.001, Tukey test). (C) By contrast, flupenthixol (FLU), another D1-selective antagonist, did not cause a statistically significant suppression of dopamine-stimulated cAMP production (*P<0.05, Tukey test). All agents were used at a concentration of 10 µmol l-1. Bars represent the mean ± S.E.M. of 5–6 samples.





Right arrow Return to article