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Fig. 10. The effect of the D1-selective antagonists SKF83566 and flupenthixol on
dopamine-stimulated glycoprotein secretion by the albumen glands of H.
duryi. The application of dopamine (50 µmol l-1) stimulated
glycoprotein secretion more than fourfold compared with control glands in
saline. (A) In the presence of SKF83566 (50 µmol l-1),
dopamine-stimulated glycoprotein secretion was significantly suppressed.
Abbreviations: CON, control; DA, dopamine; DA+SKF, dopamine + SKF83566. Bars
represent the mean ± S.E.M. of 1520 samples
(*P<0.05, Tukey test). (B) The D1-selective antagonist
flupenthixol also caused a significant inhibition of dopamine-stimulated
protein secretion in isolated albumen glands. Abbreviations: CON, control; DA,
dopamine; DA+FLU, dopamine + flupenthixol. Neither antagonist had an effect on
basal glycoprotein secretion. Bars represent the mean ±
S.E.M. of 1520 samples (*P<0.05,
Tukey test).