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Fig. 3. Time courses of the transepithelial voltage normalized to the percentage of
the control value (–38 mV and –19 mV, respectively), showing the
effects of substitution of Na+ (time period 1,
N-methylglucamine) and Cl- (time period 2, gluconate).
During the time periods indicated by w, perfusion of the anterior stomach
preparation was changed to withdrawal mode, establishing the bathing solution
also on the luminal side of the epithelium. Infusion mode was used during the
rest of the time. At the arrow, the preparation was withdrawn from the
perfusion pipette.
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