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Fig. 2. Effect of cadmium and various effectors on Na+ influx (µmol
Na+ h–1 10–6 cells) in isolated
digestive gland cells of Mytilus galloprovincialis. Cells were
treated for 30 min either with cadmium at 50 µmol l–1 or
cadmium (50 µmol l–1) + 20 nmol l–1 EIPA
(a selective inhibitor of Na+/H+ exchanger), or cadmium
(50 µmol l–1) + 20 nmol l–1 calphostin C
(a specific inhibitor of protein kinase C), or cadmium (50 µmol
l–1) + 10 µmol l–1 propranolol (a
ß-adrenergic antagonist). See Materials and methods for details. Values
are means ± S.D. of at least 4 independent
experiments. In each experiment, the tissue of four animals was used.
*Significant difference between control value and that observed
after metal treatment; 
significant difference between the
value obtained after cadmium treatment with that obtained after cadmium +
effector treatment; Dunnet's test, P<0.01.
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