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Fig. 5. Sequences of footprinted regions observed in Fig. 4. (A) Footprinting in the termination region of tRNAleu. The conserved binding sequence of mTERF (Valverde et al., 1994b) is boxed. (B) The sequence in the control region located approximately 75 nt 5' of the tRNAmet gene in an area thought to contain the L-strand promoter (Carrodeguas and Vallejo, 1997). The L strand was footprinted in both cases. Primers used were LEU 1 for A and LSP 1 for B (see Table 1 for primers). Genomic positions are indicated. Relative to naked DNA, overmethylated residues are filled squares and undermethylated residues are unfilled squares.





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