Fig. 3. (A) The effects of various inhibitors on lactate efflux from trout white muscle sarcolemmal vesicles. All vesicles were loaded with 25 mmol l^-1 lactate and 18.5 kBq ¹⁴C-lactate. Values are means ± 1 S.E.M. Control (N=5): efflux was measured in KCl/Mops buffer; STOP (N=10), efflux in ice-cold, 2.5 mmol l^-1 HgCl₂; 75 mmol l^-1 Na (N=7): efflux in 75 mmol l^-1 KCl, 75 mmol l^-1 NaCl Mops buffer; 5 mmol l^-1 CIN (N=6): efflux in KCl/Mops containing 5 mmol l^-1 -cyano-4-hydroxycinnamate; 5 mmol l^-1 SITS (N=11): efflux in KCl/Mops containing 5 mmol l^-1 4-acetoamido-4'-isothyiocyanstilbene-2,2'-disulphonic acid. ^*A significant difference (P<0.05) from the control value. (B) The influence of pH gradient on lactate efflux from trout white muscle sarcolemmal vesicles. Values are means ± 1 S.E.M. pH_i<pH_e, N=11; pH_i>pH_e, N=7, pH_i=pH_e=5.1, N=5; pH_i=pH_e=7.4, N=6. ^*A significant difference (P<0.05) from the pH_i=pH_e=7.4 value.

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