Fig. 5. Serotonin, gramine and octopamine affect the M3 activity (red lines) and action potential duration (blue lines) of eat-18 mutant pharynxes in a dosage-sensitive manner. (A) Serotonin enhances M3 activity and decreases action potential duration with an EC₅₀ of approximately 30 nmol l^-1. In the presence of 100 nmol l^-1 exogenous serotonin, gramine (B) and octopamine (C) suppress M3 activity and increase action potential duration in a dosage-sensitive manner. Values are means ± S.E.M.

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