Fig. 4. (A) Accumulation of cadmium (Cd) after 0, 3, 5 and 7 days exposure, as well as 7 days exposure followed by a 2-day depuration period in control water, in the olfactory rosette, olfactory nerve and olfactory bulb. Calculated Cd accumulation (right-hand y-axis) was determined as described in Materials and methods. All points within each tissue are statistically distinct (P<0.05) before transfer to control water (depuration period). (B) Concentration index relative to mean fish liver concentrations for the olfactory rosette, olfactory nerve and olfactory bulb. * represents a significant difference between fish exposed for 7 days and those exposed for 7 days followed by 2 days of depuration (P<0.05).

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