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Fig. 7. Effects of spontaneous muscle contraction on the membrane potential of the cardiac ganglion (CG) neuron. In each record: upper trace, the membrane potential activity recorded from Cell-6; lower trace, the myocardial tension recorded from the anterior half of the heart. Records A to E were obtained successively from a single preparation. (A) Control activity of the CG neuron and the heart muscle recorded in the normal saline solution. (B) 3 min after application of 10 µmol l-1 Joro spider toxin (JSTX). (C) 7 min after application of JSTX. The JSTX was applied for 17 min, and then the perfusion was switched to the saline containing both JSTX and tetrodotoxin (TTX). (D) 3 min after addition of 1.0 µmol l-1 TTX. (E) Bursting activity of the CG neuron recovered 3 min after washout of TTX.





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