Fig. 4. Effect of basolateral adenosine upon transepithelial currents of leech dorsal integuments. Integuments adapted to artificial pondwater (APW) or high-salinity (HSW) were clamped to 0 mV Transepithelial Na⁺ current (I_Na) was determined after equilibration (Control). Subsequently, 1 mmol l^-1 adenosine was added to the basolateral compartment and, when the short-circuit current (I_sc) had stabilized, I_Na was determined again (Adeno). Values are means ± S.E.M. (N=5). Addition of 1 mmol l^-1 adenosine to the basolateral compartment significantly increased I_sc but not I_Na in HSW-adapted integuments, ^**P<0.005. Hatched columns, transepithelial Na⁺ current; filled columns, residual non-Na⁺ currents.

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