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Fig. 1. Alignment of derived AQP3 amino acid sequences from the eel in comparison to those from other species. Dashes indicate identical residues, periods indicate spaces introduced to give an optimal alignment, bold underlinings indicate the approximate locations of membrane spanning domains (TM 1-6: Kyte and Dolittle, 1982) and wavy underlinings indicate the location of inter-transmembrane loops (A—E; Borgnia et al., 1999). Percentages represent the amino acid homology of each sequence to that of the eel. Sequences were aligned using GeneJockey II software (Biosoft). Dashes, underlining and periods were added after alignment. The EMBL/Swiss prot accession numbers for sequences were as follows: Eel (AJ319533), Xenopus (AJ131847), Rat (L35108), Mouse (AF104416) and Human (AB001325).





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