Fig. 5. MYH13 uses multiple transcription initiation sites and generates alternatively spliced mRNAs. The alternative splicing patterns of three full-length cDNAs of extraocular myosin are shown. Transcript A skips exon 2. Transcription of B and C begin downstream of A in exon 1, and they both include exon 2. The nucleotide sequence of the longest rabbit cDNA is aligned with the human gene sequence to show the predicted exon boundaries. Short stretches of the introns are shown in lower case, and the consensus splice sites are marked by underlining. The locations of the transcription start sites A, B and C are indicated by horizontal arrows, and the TATA boxes upstream of B and C are boxed. Only part of exon 3 is shown. From Briggs and Schachat (2000).

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