Fig. 5. Three-dimensional reconstructions of immediate (A) and delayed (B) PEG-treated spinal cord segments. In A, the histological data set was obtained from an animal to which PEG had been applied within 30 min of injury. (B) Three-dimensional reconstructions of a spinal cord segment for which application of PEG to the injury site was delayed for approximately 7 h. As in Fig. 4, the top images show both the normal and damaged parenchyma with the cysts removed from the image. Both spinal cord segments were markedly compressed at the epicenter of the compression injury. In the middle and bottom images, the intact parenchyma of the spinal segments is imaged. Bottom, the spinal segments have been rotated by approximately 180° in the horizontal plane from the middle image. These views emphasize the greater extent of contiguous gray and white matter through the lesions of PEG-treated cords compared with controls (see also Fig. 4). The cylindrical icon gives the relative orientation of the three-dimensional segment; gray is the rostral end and black is the caudal end. Scale bar, 1 mm
