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Fig. 4. The effects of acute hypoxia (40 mmHg=5.3 kPa) on plasma angiotensin II levels in rainbow trout (Oncorhynchus mykiss) previously infused (0.2 ml min–1) with nicotine (1.3x10–5 mol kg–1 h–1) or saline (data were combined as there were no significant differences in [angiotensin II] between the two groups) for 60 min under conditions of normoxia. An injection of saline (filled columns; N=15) or lisinopril (10–4 mol kg–1; open columns; N=15) was made prior to hypoxia at 40 min infusion. ‘Pre’ samples were taken immediately prior to the onset of hypoxia. Values are shown as means + S.E.M. An asterisk denotes a statistically significant increase (P<0.05) from the corresponding ‘Pre’ value. A dagger indicates a statistically significant difference (P<0.05) from the control value.





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