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First published online January 18, 2008
Journal of Experimental Biology 211, 400-408 (2008)
Published by The Company of Biologists 2008
doi: 10.1242/jeb.011205
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Hematological changes associated with egg production: estrogen dependence and repeatability

Emily C. Wagner1,*, Jaime S. Prevolsek2, Katherine E. Wynne-Edwards3 and Tony D. Williams4

1 Women's Health Research Institute, E204-4500 Oak Street, Box 42, Vancouver, British Columbia, V6H 3N1, Canada
2 School of Criminology, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, V5A 1S6, Canada
3 Department of Biology, Queen's University, Kingston, Ontario, Canada, K7L 3N6
4 Department of Biological Sciences, Simon Fraser University, 8888 University Drive, Burnaby, British Columbia, V5A 1S6, Canada


Figure 1
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  		Fig. 1. Reaction norms for change in hematocrit from pre-breeding to the 1-egg stage in the (A) unmanipulated (N=22), (B) estradiol-treatment (N=23), (C) sham-treatment (N=26) and (D) tamoxifen-treatment (N=18) trials. Plotted lines represent data from individual females and grey filled circles represent the mean hematocrit calculated at each stage.

 

Figure 2
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  		Fig. 2. The relationship between pre-breeding and 1-egg hematocrit among individual females in the (A) unmanipulated trial (N=22), (B) estradiol-treatment (N=23), (C) sham-treatment (N=26) and (D) tamoxifen-treatment (N=18) experimental trials. Significant regression lines are presented with 95% confidence intervals (dotted lines).

 

Figure 3
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  		Fig. 3. The change in hematocrit from pre-breeding to the 1-egg stage as a function of pre-breeding hematocrit for (A) unmanipulated (N=22), (B) estradiol (N=23), (C) sham (N=26) and (D) tamoxifen (N=18) experimental trials. Regression lines are presented with 95% confidence intervals (dotted lines).

 

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