QUICK SEARCH:   [advanced] Author: Keyword(s):
Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents

First published online November 14, 2008
Journal of Experimental Biology 211, 3759-3763 (2008)
Published by The Company of Biologists 2008
doi: 10.1242/jeb.021089

This Article Summary Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Wang, T. Articles by Hicks, J. W. Search for Related Content PubMed PubMed Citation Articles by Wang, T. Articles by Hicks, J. W. Social Bookmarking                         What's this?

Changes in pulmonary blood flow do not affect gas exchange during intermittent ventilation in resting turtles

Tobias Wang^1,2,* and James W. Hicks²

¹ Zoophysiology, Department of Biological Sciences, University of Aarhus, 8000 Aarhus C, Denmark
² Department of Ecology and Evolutionary Biology, University of California at Irvine, Irvine, CA 92697, USA

View larger version (23K): [in this window] [in a new window]   Fig. 1. An example of ventilation and blood flows in a turtle instrumented with flow probes on the left aortic arch (LAo) and the left pulmonary artery, as well as a vascular occluder around the common pulmonary artery. During the first 60 min, pulmonary blood flow (pul) and heart rate (fH) increased substantially during ventilation, and caused the development of a net left–to-right (L–R) cardiac shunt pattern. This rise in pul was then prevented by partial occlusion of the common pulmonary by inflation of the vascular occluder for the following 60 min. As a consequence, a net cardiac right-to-left (R–L) shunt prevailed even during ventilation. Blood flows and ventilation are also shown during 60 min after releasing the occlusion.

View larger version (13K): [in this window] [in a new window]   Fig. 2. Blood flows and cardiac shunt pattern before, during and after partial occlusion of the common pulmonary artery. (A) Mean pulmonary blood flow (pul); (B) mean systemic blood flow (sys); (C) pul/sys. Values are means ±1 s.e.m. (N=5) over 10 min periods. Values significantly different from control conditions are marked with an asterisk (P<0.05).

View larger version (17K): [in this window] [in a new window]   Fig. 3. Ventilation and gas exchange before, during and after partial occlusion of the common pulmonary artery. (A) Pulmonary ventilation (Ve); (B) oxygen uptake (O2); (C) CO2 excretion (CO2) (D) respiratory gas exchange ratio (RE). Values are means ±1 s.e.m. (N=5) over 10 min period. Values significantly different from control conditions are marked with an asterisk (P<0.05). No mean values during manipulation are significantly different than those obtained during the preceding control period.

View larger version (33K): [in this window] [in a new window]   Fig. 4. Oxygen uptake (O2), CO2 excretion (CO2) and the respiratory gas exchange ratio (RE) as a function of minute ventilation (Ve, left panel), pulmonary blood flow (pul middle panel) and pul/sys (right panel). Open circles represent periods of partial occlusion of the pulmonary artery, and closed circles represent pre- and post-occlusion. Each symbol represents the mean value determined every 10 min, during a three hour experimental protocol.

CiteULike

Complore

Connotea

Del.icio.us

Digg

Reddit

Technorati

Twitter