spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online May 2, 2008
Journal of Experimental Biology 211, 1587-1593 (2008)
Published by The Company of Biologists 2008
doi: 10.1242/jeb.016725
This Article
Right arrow Summary Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Geister, T. L.
Right arrow Articles by Fischer, K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Geister, T. L.
Right arrow Articles by Fischer, K.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Effects of the NMDA receptor antagonist MK-801 on female reproduction and juvenile hormone biosynthesis in the cricket Gryllus bimaculatus and the butterfly Bicyclus anynana

Thorin L. Geister1,*, Matthias W. Lorenz1, Klaus H. Hoffmann1 and Klaus Fischer1,2

1 Department of Animal Ecology I, University of Bayreuth, D-95440 Bayreuth, Germany
2 Zoological Institute and Museum, University of Greifswald, D-17487 Greifswald, Germany


Figure 1
View larger version (13K):
[in this window]
[in a new window]

  		Fig. 1. Number (A) and size (B) of eggs produced over time by female Bicyclus anynana treated with different concentrations of MK-801. Injections of MK-801 (controls were injected with Ringer solution only) were given on days 0, 2 and 6 of adult life. To improve clarity, no standard errors are presented (N=38–40).

 

Figure 2
View larger version (6K):
[in this window]
[in a new window]

  		Fig. 2. Effects of MK-801 on the cumulative survival probability of Bicyclus anynana females. Injections of MK-801 (control: Ringer solution) were applied on days 0, 2 and 6 of adult life (N=38–40).

 

Figure 3
View larger version (11K):
[in this window]
[in a new window]

  		Fig. 3. Number (A) and size (B) of eggs produced over time by female Gryllus bimaculatus treated with different concentrations of MK-801. Injections of MK-801 (controls were injected with Ringer:DMSO 1:1, v/v) were given on days 0 and 3. To improve clarity, no standard errors are presented (N=34–37).

 

Figure 4
View larger version (11K):
[in this window]
[in a new window]

  		Fig. 4. Effects of MK-801 (MK), juvenile hormone mimics [pyriproxyfen (Pyr) or methoprene (Met)], both compounds or the pure solvent (control) on early fecundity in Bicyclus anynana (A; N=70–77) and Gryllus bimaculatus (B; N=33–36). Values are means ±1 s.e.m. Different letters above bars indicate significant differences between groups (Tukey's HSD after ANOVA).

 

Figure 5
View larger version (4K):
[in this window]
[in a new window]

  		Fig. 5. Dose–response curve for in vitro inhibition of juvenile hormone (JH) synthesis by MK-801 in single Gryllus bimaculatus corporus allatum. Values are given relative to the first incubation rates of each corporus allatum (N=20–35, but for 10–3 and 10–6 mol l–1 N=10). Controls released JH III in the second incubation at a rate of 26.8±1.8 pmol h–1.

 

Figure 6
View larger version (6K):
[in this window]
[in a new window]

  		Fig. 6. Effects of MK-801 and time on in vivo juvenile hormone titres in the haemolymph of Gryllus bimaculatus females (N=21–24). Females were injected with MK-801 on days 0 and 3 following ecdysis. Haemolymph was sampled 3 and 24 h after the last injection. The value for the control group on day 3 was set to 100%. Given are means ±1 s.e.m.

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?



© The Company of Biologists Ltd 2008