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First published online November 17, 2005
Journal of Experimental Biology 208, 4445-4450 (2005)
Published by The Company of Biologists 2005
doi: 10.1242/jeb.01920

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The absence of mitochondrial DNA diversity among common laboratory inbred mouse strains

Ji-gang Dai¹, Jia-xin Min^1,*, Ying-bin Xiao¹, Xia Lei¹, Wen-hao Shen¹ and Hong Wei²

¹ Department of Thoracic Surgery, Xinqiao Hospital, The Third Military Medical University, Chongqing 400037, China
² Center of Laboratory Animal, The Third Military Medical University, Chongqing 400038, China

View larger version (76K): [in a new window]   Fig. 1. Restriction patterns of amplified fragments. Restriction patterns of (A) mtDNA D-loop XbaI; (B) tRNAIle+GlN+Met StuI; (C) ND3 fragment AluI. Mouse strains: lanes 1, TA2; 2, 615; 3, T739; 4, BALB/c; 5, C3H; 6, C57BL/6J; 7, DBA/2. The standard marker (M) of Huamei Company was adopted as the molecular mass standard to determinate the length of enzyme-cutting fragments.

View larger version (113K): [in a new window]   Fig. 2. SSCP analysis of D-loop fragment. (A) SSCP analysis of D-loop 5' fragment; (B) SSCP analysis of D-loop 3' fragment. Mouse strains: lanes 1, T739; 2, TA2; 3, 615; 4, BALB/c; 5, C3H; 6, C57BL/6J; 7, DBA/2.