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First published online June 6, 2005
Journal of Experimental Biology 208, 2447-2458 (2005)
Published by The Company of Biologists 2005
doi: 10.1242/jeb.01631
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Maximal metabolic rates during voluntary exercise, forced exercise, and cold exposure in house mice selectively bred for high wheel-running

Enrico L. Rezende*, Mark A. Chappell, Fernando R. Gomes, Jessica L. Malisch and Theodore Garland, Jr

Department of Biology, University of California, Riverside, California 92521, USA



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Fig. 1. Relationship between maximum rates of oxygen consumption (O2max; A) and running speeds (B) during voluntary wheel-running and forced exercise on the treadmill. Each value represents one of 47 female mice measured over 4 consecutive trial days (see Materials and methods and Table 1). Dotted lines indicate equal values. Each point represents the mean highest 60 s recorded for each individual.

 


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Fig. 2. (A) Maximum 1 min average O2 during voluntary exercise on the wheels (O2max,W), forced exercise on the treadmill (O2max,T), and acute cold exposure in heliox (O2max,H), in 47 females from S and C lines. (B) Maximum running speeds obtained on the treadmill (SpdMax,T) and on the wheel (SpdMax,W) for these same individuals. Values for oxygen consumption are adjusted means from SAS PROC MIXED for a female of 25.3 g; values for speed are not adjusted for mass (see text). Asterisks indicate significant differences between S and C lines (P<0.05, Table 3). Vertical bars indicate ± 1 S.E.M.

 


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Fig. 3. Relationship between maximum running speeds and O2max during (A) voluntary activity in the wheel and (B) forced exercise on the treadmill, obtained for 47 female mice. Dotted lines show least-squares linear regressions for raw data (i.e. not corrected for covariates). Correlations between O2max and speed after accounting for body mass and age are listed in Table 5.

 





© The Company of Biologists Ltd 2005