First published online December 15, 2004
Journal of Experimental Biology 208, 105-112 (2005)
Published by The Company of Biologists 2005
doi: 10.1242/jeb.01349
The interplay of cutaneous water loss, gas exchange and blood flow in the toad, Bufo woodhousei: adaptations in a terrestrially adapted amphibian
Warren W. Burggren1,* and
Timothy Z. Vitalis2
1 Department of Biological Sciences, University of North Texas, PO Box
305189, Denton, TX 76203, USA
2 Biotechnology Laboratory, University of British Columbia, 6174 University
Boulevard, Vancouver BC V6T 1Z3, Canada

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Fig. 1. Effects of the injection of saline, isoproterenol (5 mg kg-1)
and phentolamine (2 mg kg-1) on heart rate (A) and systolic and
diastolic blood pressure (B) in the toad Bufo woodhousei. Values for
each toad from hour 1, 3 and 5 following injection were averaged into a single
data point for each condition, which were then averaged and plotted as means
± 1 S.D. (N=5 toads).
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Fig. 2. Time course of dehydration and rehydration rates in control toads (Bufo
woodhousei) and those treated with isoproterenol or phentolamine. Means
± 1 S.D. are plotted. Note the time-scale
difference between the two plots, which reveals a much higher rate of
rehydration than dehydration (see also
Table 1). N=11 toads
for each of the three treatments.
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© The Company of Biologists Ltd 2005